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So far it is difficult to demonstrate any link, although the best studies do suggest some association between mobile phone use and cancer, the team led by Dr. Seung-Kwon Myung of South Korea's National Cancer Center found.

Myung and colleagues at Ewha Womans University and Seoul National University Hospital in Seoul and the University of California, Berkeley, examined 23 published studies of more than 37,000 people in what is called a meta-analysis.

They found results often depended on who conducted the study and how well they controlled for bias and other errors.

"We found a large discrepancy in the association between mobile phone use and tumor risk by research group, which is confounded with the methodological quality of the research," they wrote in the Journal of Clinical Oncology.

The use of mobile and cordless phones has exploded in the past 10 years to an estimated 4.6 billion subscribers worldwide, according to the UN International Telecommunication Union.

Research has failed to establish any clear link between use of the devices and several kinds of cancer.
Radio frequency exposure from cell phone use does not appear to increase the risk of developing brain cancers by any significant amount, a study by University of Manchester scientists suggests. The researchers used publicly available data from the UK Office of National Statistics to look at trends in rates of newly diagnosed brain cancers in England between 1998 and 2007.

The study, published in the journal Bioelectromagnetics, reported no statistically significant change in the incidence of brain cancers in men or women during the nine-year time period under observation.

"Cell phone use in the United Kingdom and other countries has risen steeply since the early 1990s when the first digital cell phones were introduced," said lead researcher Dr Frank de Vocht, an expert in occupational and environmental health in the University of Manchester's School of Community-Based Medicine.

"There is an on-going controversy about whether radio frequency exposure from cell phones increases the risk of brain cancer. Our findings indicate that a causal link between Cell Phone use and cancer is unlikely because there is no evidence of any significant increase in the disease since their introduction and rapid proliferation "

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